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🌏 | AstraZeneca Questions about New Corona Vaccine Trial or Data


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AstraZeneca Questions about New Corona Vaccine Trial or Data

 
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Others have pointed out significant gaps in the data AstraZeneca has released so far.
 

[Reuters] – Solio CEO of AstraZeneca, a major British pharmaceutical company, said on the XNUMXth, UK Oc ... → Continue reading

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AstraZeneca

AstraZeneca(British: AstraZeneca plc) IsUK-CambridgeIs a pharmaceutical company headquartered in.London Stock Exchange,Nasdaq Stockholm,New York Stock ExchangeListed company (LSEAZN,Nasdaq Nordic AZN,NYSEAZN).1999年A leading British chemical company HEREZeneca separated from the pharmaceutical department fromスウェーデンWas born by the merger of Astra, the largest pharmaceutical manufacturer in Northern Europe.

Japanese corporation

As a subsidiary in Japan,OsakaKitaOf OfukaGrand Front OsakaWithinAstraZeneca Corporation(AstraZeneca KK) Headquarters. AlsoTokyoChiyoda WardMarunouchiThe Tokyo branch office is located in the main building of the Marunouchi Trust Tower.

History

  • 1974å¹´April: Established ICI Pharma Co., Ltd. (Zeneca UK and Sumitomo Chemical Co., Ltd. (currently)Sumitomo Chemical) Established in partnership.After that, the company name was changed to Zeneca Co., Ltd. )
  • 1975å¹´April: Established Fujisawa Astra Co., Ltd. (Swedish company Astra and Fujisawa Pharmaceutical Co., Ltd. (currently)Astellas Pharma) Established in partnership.After that, the company name was changed to Astra Japan Co., Ltd. )
  • 1998å¹´March:MaibaraFactory operation started.It is a manufacturing base in Japan.
  • 2000å¹´January: AstraZeneca Co., Ltd. merges with AstraZeneca Co., Ltd.

Main products

  • Cancer system
    • Casodex:Prostate cancerTherapeutic agent (antihormonal drug)
    • Zoladex: Prostate cancer/premenopausal breast cancer drug (antihormonal drug)
    • Zaitiga: Prostate cancer drug (CYP17 inhibitor)
    • Nolvadex : Breast cancerTherapeutic agent (antihormonal drug)
    • Arimidex: Postmenopausal breast cancer drug (inhibitor)
    • Fesolodex: Breast cancer drug (antiestrogenAgent)
    • Iressa: Inoperable or recurrentNon-small cell lung cancerRemedy (Epidermal growth factor receptor (EGFR) Tyrosine kinaseInhibitor)
    • Rim parza:breast cancer·Ovarian cancerTherapeutic agent (PARP inhibitor)
    • Tagrisso: Inoperable or recurrent non-small cell lung cancer drug positive for EGFR mutation (anti-neoplastic agent/tyrosine kinase inhibitor)
    • Imfinzi: maintenance therapy (human anti-human PD-L1 monoclonal antibody) after definitive chemoradiotherapy for unresectable locally advanced non-small cell lung cancer
  • Endocrine system
    • Fosiga: Type 2 diabetes therapeutic agent (selective SGLT2 inhibitor)
    • Subcutaneous injection of vidurion: therapeutic agent for type 2 diabetes (GLP-1 receptor agonist)
  • Cardiovascular system
  • Respiratory system
    • Palmi Court Turbuhaler:Bronchial asthmaTherapeutic agent (inhalationsteroidmedicine: Budesonide)
    • Pulmicort inhalation solution: Bronchial asthma drug (inhaled corticosteroid: budesonide)
    • Symbi coatTurbuhaler: Drug for treatment of bronchial asthma and chronic obstructive pulmonary disease (of inhaled corticosteroids)BudesonideAnd long-acting inhaled β2 stimulantFormoterolFormulation) → In JapanAstellas PharmaSold by
    • Fasenra Subcutaneous Injection: Bronchial asthma drug (humanized anti-IL-5 receptor α monoclonal antibody preparation)
  • Digestive system
  • central nervous system
    • Zomig:Migraine() 5-HT1B / 1DReceptor agonist → Transferred to Sawai Pharmaceutical and transferred to sales
  • Anesthesia system → Sales transferred to Aspen Japan
    • Xylocaine:localAnesthetic, Antiarrhythmic agents
    • Anapain: long-acting local anesthetic
    • Marcaine: spinal anesthetic, long-acting local anesthetic
    • Carbokine: local anesthetic
    • Diprivan: General anesthesia and analgesics

Lawsuit

2002å¹´,Anti-cancer agentIs the epidermal growth factor inhibitor Iressa (generic name:Gefitinib) Was obtained in Japan for the first time in the world, but side effects became a problem.2013å¹´, At the 4th Gefitinib Study Group of the Ministry of Health, Labor and WelfareGuidelinesI decided to continue using Iressa by promoting the publicity of.

Scandal

In 2010, AstraZeneca illegally marketed Seroquel for off-label use in the elderly and in children who increase the risk of death, and was fined $5.2 million.[10][11].

Involved in the development of a new coronavirus vaccine

Oxford UniversityIs advancingNew coronavirus vaccineParticipated in the development and manufacturing of candidates. By May 2020, it had a capacity to produce 5 billion vaccines. Funds for manufacturing preparation, etc.US Biomedical Advanced Research and Development AgencyFrom over $10 billion in support[12].

Concluded a comprehensive cooperation agreement with Osaka Prefecture

In 2021, Osaka Prefecture announced the conclusion of a comprehensive cooperation agreement with AstraZeneca Co., Ltd.[13].

footnote

  1. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 143 Page> Consolidated Statement of Financial Position> Equity Capital and reserves exclusively to equity holders of the Company Archived August 2012, 5, at the Wayback Machine.
  2. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 205Page> Shareholder Information> Number of shares Archived August 2012, 5, at the Wayback Machine.
  3. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 142Page> Consolidated Statement of Comprehensive Income> Revenue Archived August 2012, 5, at the Wayback Machine.
  4. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 142Page Consolidated Statement of Comprehensive Income> Consolidated Statement of Comprehensive Income> Operating profit Archived August 2012, 5, at the Wayback Machine.
  5. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 142Page> Consolidated Statement of Comprehensive Income> Total comprehensive income for the period Archived August 2012, 5, at the Wayback Machine.
  6. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> Page> Consolidated Statement of Financial Position> Net assets Archived August 2012, 5, at the Wayback Machine.
  7. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 143Page> Consolidated Statement of Financial Position> Total assets Archived August 2012, 5, at the Wayback Machine.
  8. ^ AstraZeneca> Investors> Annual Reports> Annual Report and Form 20-F Information 2011> 3Page> Our business> employees worldwide Archived August 2012, 5, at the Wayback Machine.
  9. ^ a b c d e AstraZeneca Corporation Announcement of financial results for the 45th term
  10. ^ Maia Szalavitz Sept (September 2012, 9). “Top 10 Drug Company Settlements”. TIME.com. http://healthland.time.com/2012/09/17/pharma-behaving-badly-top-10-drug-company-settlements/ 2013/2/23Browse. 
  11. ^ "Pharmaceutical Giant AstraZeneca to Pay $ 520 Million for Off-label Drug Marketing”. Justice.gov (November 2010, 4). 2012/11/30Browse.
  12. ^ "UK AstraZeneca receives support from US for vaccine development of new corona”. Bloomberg (June 2020, 5). 2020/5/21Browse.
  13. ^ "Press Release [Public-Private Partnership] Conclude a comprehensive collaboration agreement with AstraZeneca Co., Ltd.”. Osaka Prefectural Government [Osaka Prefectural Government] (January 2021, 1). 2021/1/20Browse.

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