Osaka University Discovers Genes That Disturb Normal Brain Development in Children with Down Syndrome
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By focusing on astrocytes, which play a major role in the maintenance and pathological changes of nerve cells, and inducing and examining astrocyte progenitor cells in the Down's syndrome cell model, astrocytes are overgrown in Down's syndrome. We found that there are two responsible genes, DYRK1A and PIGP.
A research group led by Dr. Keiji Kawatani and Associate Professor Koji Kitabatake of Osaka University Children's Surgical Hospital has applied genome editing technology to human iPS. → Continue reading
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